Faytamiinkan ayaa kor u qaadi kara Difaaca inta lagu jiro COVID

Faafida COVID-19 waxay dhammaanteen naga welwelsan tahay kor u qaadista xasaanadda iyo adkeysiga, maadaama aan sidoo kale maareyno walaaca iyo xitaa dhaawacyada dhacdooyinkan. Fahamka sida buufiska iyo jugtu u saamayso caafimaadkeena iyo xasaanaddeena waxay wargelineysaa tallaabooyinka ka hortagga ah ee aan qaadi karno.

Daraasad cilmi-baaris dib-u-eegis ah oo dib-u-eegis lagu sameeyay ayaa lagu ogaaday in dadka heerarka Vitamin D aad u hooseeya ay aad ugu badan tahay inay qaadaan COVID-19 (Meltzer et al, 2020). Kordhinta Faytamiin D oo ah qiyaas ilaalin waa mid aan qaali ahayn waxaana laga yaabaa inay si gaar ah muhiim ugu tahay dadka waayeelka ah, Afrikaanka Ameerikaanka ah, Isbaanishka, iyo dadka ku nool cimilada waqooyi oo si gaar ah hoos ugu dhacay cillad (Cashman, K.D 2020).

Intii lagu jiray masiibada, jawaabeyaasha ugu horreeya iyo dadweynaha guudba waxay la kulmeen culeys iyo walaac aad u sarreeya. Dr. Holick oo ka tirsan Jaamacadda Boston University School of Medicine wuxuu soo jeedinayaa in dayactirka heerarka serum ku filan ee Faytamiin D ay lagama maarmaan u tahay kor u qaadista xasaanadda (Charoenngam, N.; Holick, M.F., 2020). Dhab ahaantii, waxa aan ugu yeerno Vitamin D ma aha fitamiin dhab ah. Taa bedelkeeda, waa neurohormone lagu soo habeeyay kolestaroolka jirka iyo soo -gaadhista iftiinka qorraxda ee maqaarka. Ka sokow kaabayaasha, ilaha ugu waaweyn ee fitamiin D waa kalluunka dufanka leh, beerka xoolaha, saliida kalluunka, iyo ukunta (Bivona, G., Agnello, L., iyo Ciaccio, M., 2018). Sidaa darteed, khudaarleyda iyo vegans -ka ayaa u nugul yaraanta.

Qiyaasta shaybaarka ugu fiican ee lagu go'aamiyo yaraanshaha Vitamin D waa serum, 25-hydroxy vitamin D, baaritaan dhiig oo la codsan karo inuu qayb ka yahay baaritaanka dhiigga sannadlaha ah.

Waxa kale oo muhiim ah in la fahmo in kasta oo walbahaarka ba'an uu kor u qaadi karo shaqada difaaca, walbahaarka dabadheeraadku uu xakameeyo (McEwen, 2000). Cadaadiska joogtada ah wuxuu soo saaraa falcelinta wadnaha, difaaca jirka, iyo isbeddelada endocrinologic (Kiecolt-Glaser, Malarkey, Cacioppo, iyo Glaser, 1994). Waxay sidoo kale si xun u saamayn kartaa isbeddelada shaqada iyo qaabdhismeedka maskaxda waxayna kordhisaa firfircoonida difaaca bukaanka qaba PTSD (McEwen, 2000). Tusaale ahaan, waxaa la wada ogsoon yahay in culeysku uu kicin karo cudurrada iswada sida rheumatoid arthritis -ka iyo in dadka qaba PTSD ay halis sare ugu jiraan shaqeynta autoimmune (Boscarino, 2004).

Xaaladahan, hab -dhiska difaaca jidhku wuxuu noqdaa mid aad u firfircoon, oo ka tarjumaya heer kale oo si xad -dhaaf ah oo nidaamsan uga falceliya hanjabaad ka dib dhacdooyinka naxdinta leh. Dadka qaba PTSD waxay kordhiyeen heerarka calaamadaha bararka iyo kordhinta falcelinta tijaabooyinka maqaarka ee antigen (Pace iyo Heim, 2011). Markaa maareynta walaaca inta lagu jiro COVID-19 adoo adeegsanaya waxqabadyo kala duwan, oo ay ku jiraan cuntada, jimicsiga, iyo maanka, oo ay weheliso hurdo badan, dhammaantood waxay bixiyaan waddooyin muhiim ah si kor loogu qaado xasaanadda.

Wax badan ka baro xasaanadda waqtiyada COVID iyada oo loo marayo koorsadayda bilaashka ah, Talooyinka Nafaqada iyo Is-dhexgalka Inta lagu jiro COVID-19.

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Cashman, KD Faytamiin D Yaraanshaha: Qeexidda, Ka -hortagga, Sababaha, iyo Xeeladaha Wax -ka -qabashada. Cadka Calcif Int 106, 14–29 (2020). https://doi.org/10.1007/s00223-019-00559-4.

Charoenngam, N .; Holick, M.F. Saamaynta Immunologic ee Faytamiin D ee Caafimaadka Aadanaha iyo Cudurrada. Nafaqooyinka 2020, 12, 2097.

David O Meltzer, Thomas J Best, Hui Zhang, Tamara Vokes, Vineet Arora, Julian Solway med Rxiv 2020.05.08.20095893; doi: https://doi.org/10.1101/2020.05.08.20095893.

Kiecolt-Glaser, J. K., Malarkey, WB, Cacioppo, J. T., & Glaser, R. (1994). Xiriirrada shaqsiyeed ee walaaca leh: Shaqada difaaca jirka iyo endocrine. In R. Glaser & J. K. Kiecolt-Glaser (Eds.), Buug-gacmeedka walaaca iyo xasaanadda aadanaha (bogga 321–339). SanDiego, CA: Saxaafadda Waxbarashada.

McEwen, BS (2000). Cudurka neerfaha ee walaaca: Laga soo bilaabo serendipity ilaa ku habboonaanta kiliinikada. Cilmi -baarista Maskaxda, 886 (1-2), 172–188.

Pace, TW, & Heim, C. M. (2011). Dib -u -eegis kooban oo ku saabsan cilmi -nafsiga maskaxda ee jirro -xumada walaaca ka dib: Laga soo bilaabo qodobbada halista ah ilaa cudurrada caafimaadka. Dabeecadda Maskaxda iyo Xasaanadda, 25 (1), 6-13.